Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 15/20 | 0.53 |
| ▸ | CCKBR | P32239 | 14/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | MC1R | Q01726 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405715 | 0.89 | CCKAR (0.51) | CCKARCCKBR | |
| SCHEMBL8405020 | 0.83 | CCKAR (0.56) | CCKARCCKBRMC4RMC1R | |
| SCHEMBL8405015 | 0.82 | CCKAR (0.48) | CCKARCCKBRMC4RMC1R | |
| SCHEMBL7751752 | 0.81 | CCKAR (0.70) | CCKARCCKBR | |
| SCHEMBL8402034 | 0.79 | CCKAR (0.57) | CCKARCCKBR | |
| SCHEMBL8095874 | 0.78 | CCKAR (0.51) | CCKARCCKBR | |
| SCHEMBL8404998 | 0.78 | CCKAR (0.55) | CCKARCCKBR | |
| SCHEMBL8402276 | 0.76 | CCKAR (0.59) | CCKARCCKBRMC4RMC1R | |
| SCHEMBL8806294 | 0.76 | CCKAR (0.52) | CCKARCCKBR | |
| SCHEMBL8406827 | 0.75 | CCKAR (0.55) | CCKARCCKBRMC4RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756602-B1 | CCK OR GASTRIN MODULATING 5-HETEROCYCLIC-1,5-BENZODIAZEPINES | GLAXO WELLCOME INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0756602-A1 | CCK OR GASTRIN MODULATING 5-HETEROCYCLIC-1,5-BENZODIAZEPINES | GLAXO WELLCOME INC. (US) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995028419-A1 | CCK OR GASTRIN MODULATING 5-HETEROCYCLIC-1,5-BENZODIAZEPINES | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |