Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.76 |
| ▸ | CTSL | P07711 | 16/20 | 0.76 |
| ▸ | CTSS | P25774 | 14/20 | 0.76 |
| ▸ | CTSB | P07858 | 6/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442096 | 0.93 | CTSK (0.80) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7160147 | 0.87 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7446016 | 0.82 | CTSK (0.82) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7159024 | 0.82 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7445997 | 0.82 | CTSK (0.82) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7445330 | 0.81 | CTSK (0.88) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7320307 | 0.81 | CTSK (0.83) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7447692 | 0.81 | CTSK (0.80) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7444898 | 0.81 | CTSK (0.83) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7444722 | 0.81 | CTSK (0.83) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959123-A | REACATING SUBSTITUTED AMINO ACID WITH 3-AMINO-4-SUBSTITUTED-AZETIDINE-2-ONE COMPOUND TO FORM 3, 4-DISUBSTITUTED-AZETIDINE-2-ONE COMPOUND; USEFUL FOR TREATING MUSCULAR DYSTROPHY, ARTHRITIS, VIRAL AND PARASITIC INFECTIONS | SYNPHAR LABORATORIES, INC. (CA) | 1999-09-28 | — | — | US | disclosed |