SCHEMBL8402145

SCHEMBL8402145

CCC1=Cc2c(-c3ccc([Si](C)(C)C)cc3)cccc2C1C[SiH2]CC1C(CC)=Cc2c(-c3ccc([Si](C)(C)C)cc3)cccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3818126 0.85 PDCD1 (0.31)
SCHEMBL8405815 0.85
SCHEMBL4001907 0.84 PDCD1 (0.30)
SCHEMBL7110783 0.82 BRD4 (0.33)
SCHEMBL3997088 0.81 BRD4 (0.33)
SCHEMBL7109583 0.81 ABCB1 (0.30)
Hydrochloric Acid SCHEMBL6380724 0.80 PTAFR (0.31)
SCHEMBL8165812 0.80 BRD4 (0.31)
Hydrochloric Acid SCHEMBL27476744 0.80
SCHEMBL7006278 0.79 GSTP1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924322-A1 Conjugate fibers and non-woven fabrics therefrom Mitsui Chemicals, Inc. (JP) 1999-06-23 EP disclosed