Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402077 | 0.93 | CCKBR (0.64) | CCKBR | |
| SCHEMBL8920118 | 0.92 | CCKBR (0.57) | CCKBR | |
| SCHEMBL8403235 | 0.91 | CCKBR (0.52) | CCKBR | |
| SCHEMBL8921630 | 0.88 | CCKBR (0.54) | CCKBR | |
| SCHEMBL8921110 | 0.87 | CCKBR (0.56) | CCKBR | |
| SCHEMBL8922075 | 0.86 | CCKBR (0.58) | CCKBR | |
| SCHEMBL8924316 | 0.86 | CCKBR (0.53) | CCKBR | |
| SCHEMBL8920646 | 0.85 | CCKBR (0.57) | CCKBR | |
| SCHEMBL8921091 | 0.85 | CCKBR (0.52) | CCKBR | |
| SCHEMBL8920014 | 0.84 | CCKBR (0.53) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0711283-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995003281-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-02-02 | — | — | WO | disclosed |