Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 5/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.64 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.64 |
| ▸ | GSR | P00390 | 2/20 | 0.56 |
| ▸ | GRM8 | O00222 | 1/20 | 0.56 |
| ▸ | GRM6 | O15303 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norvaline SCHEMBL542602 | 1.00 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Norvaline SCHEMBL17449755 | 1.00 | — | — | |
| Norvaline SCHEMBL38405 | 1.00 | — | — | |
| Norvaline SCHEMBL197812 | 1.00 | — | — | |
| Norvaline SCHEMBL38404 | 1.00 | — | — | |
| Norvaline SCHEMBL21114359 | 1.00 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Norvaline SCHEMBL28670644 | 0.97 | SLC1A2 (0.61) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Norvaline SCHEMBL28394825 | 0.97 | — | — | |
| Norvaline SCHEMBL30692359 | 0.97 | — | — | |
| Norvaline SCHEMBL4155453 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183093-A1 | INHIBITORS OF VIRUSES | UNIVERSITY OF KANSAS (US) | 2016-11-17 | — | — | WO | disclosed |
| US-8143448-B2 | Process for the preparation of (3S)-3-amino-N-cyclopropyl-2-hydroxyalkanamide derivatives | VIROBAY, INC. (US) | 2012-03-27 | — | — | US | disclosed |