Norvaline

Norvaline

SCHEMBL542602

CCCC(N)C(=O)O.CCC[C@H](N)C(=O)O

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC1A2 P43004 5/20 0.64
▸ SLC1A1 P43005 5/20 0.64
▸ SLC1A3 P43003 4/20 0.64
▸ GRIK1 P39086 4/20 0.64
▸ GRIK2 Q13002 4/20 0.64
▸ GSR P00390 2/20 0.56
▸ GRM8 O00222 1/20 0.56
▸ GRM6 O15303 1/20 0.56
▸ GRIN2D O15399 1/20 0.56
▸ GRIN3B O60391 1/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ GRM5 P41594 1/20 0.56
▸ GRIA1 P42261 1/20 0.56
▸ GRIA2 P42262 1/20 0.56
▸ GRIA3 P42263 1/20 0.56
▸ GRIA4 P48058 1/20 0.56
▸ GRIN1 Q05586 1/20 0.56
▸ GRIN2A Q12879 1/20 0.56
▸ GRIK3 Q13003 1/20 0.56
▸ GRIN2B Q13224 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Norvaline SCHEMBL17449755 1.00 — —
Norvaline SCHEMBL840389 1.00 SLC1A2 (0.64) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
Norvaline SCHEMBL38405 1.00 — —
Norvaline SCHEMBL197812 1.00 — —
Norvaline SCHEMBL38404 1.00 — —
Norvaline SCHEMBL21114359 1.00 SLC1A2 (0.64) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
Norvaline SCHEMBL28670644 0.97 SLC1A2 (0.61) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
Norvaline SCHEMBL28394825 0.97 — —
Norvaline SCHEMBL30692359 0.97 — —
Norvaline SCHEMBL4155453 0.97 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120034364-A1 USE OF PEPTIDES FOR IMPARTING KOKUMI AJINOMOTO CO., INC. (JP) 2012-02-09 — — US disclosed
EP-2415359-A1 USE OF PEPTIDE FOR IMPARTING BODY TASTE Ajinomoto Co., Inc. (JP) 2012-02-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034364-A1 USE OF PEPTIDES FOR IMPARTING KOKUMI GIPR, GABRA6, GABRB1 SLC1A2 325/4885SLC1A1 380/4885SLC1A3 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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