Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404343 | 0.76 | HTT (0.36) | CHRM1CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL8402611 | 0.74 | CHRM1 (0.51) | CHRM1CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL8402589 | 0.72 | CHRM2 (0.55) | CHRM1CHRM2CHRM3 | |
| SCHEMBL7613541 | 0.72 | CHRM1 (0.58) | CHRM1CHRM2CHRM3 | |
| SCHEMBL661974 | 0.71 | CHRM2 (0.84) | CHRM1CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL9342146 | 0.71 | CHRM1 (0.53) | CHRM1CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL6777862 | 0.70 | CHRM1 (0.43) | CHRM1CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL7420422 | 0.70 | CHRM1 (0.48) | CHRM1CHRM2CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL8872571 | 0.70 | CHRM2 (0.82) | CHRM1CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL8874947 | 0.70 | CHRM2 (0.62) | CHRM1CHRM2CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36374-E | 1,2,3-triazole and tetrazole substituted piperidine or tetrahydropyridine compounds useful as acetylcholine agonists | H. LUNDBECK, A/S (DK) | 1999-11-02 | — | — | US | disclosed |
| EP-0296721-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-23 | — | — | EP | disclosed |
| US-4925858-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1990-05-15 | — | — | US | disclosed |
| US-4866077-A | TREATMENT OF NERVOUS SYSTEM DISORDERS SUCH AS ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1989-09-12 | — | — | US | disclosed |
| EP-0296721-A2 | Heterocyclic compounds | H. LUNDBECK A/S (DK) | 1988-12-28 | — | — | EP | disclosed |