Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30001109 | 0.83 | KCNN4 (0.46) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL8402762 | 0.81 | ALDH1A1 (0.62) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL31186401 | 0.81 | ALDH1A1 (0.62) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL15367604 | 0.80 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL11044633 | 0.79 | ALDH1A1 (0.59) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL3369246 | 0.79 | ALDH1A1 (0.59) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL4074517 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL31189216 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL4564120 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL3369891 | 0.77 | ALDH1A1 (0.56) | ALDH1A1ALOX15CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730573-B1 | IODINATED DERIVATIVES, PREPARATION AND USE THEREOF AS CONTRAST AGENTS IN X-RAY RADIOLOGY | GUERBET SA (FR) | 1999-06-30 | — | — | EP | disclosed |
| US-5709846-A | Iodinated derivatives, their preparation and their use as contrast agents in x-ray radiology | GUERBET S.A. (FR) | 1998-01-20 | — | — | US | disclosed |