Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | CASP1 | P29466 | 5/20 | 0.35 |
| ▸ | CASP7 | P55210 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179206 | 0.82 | TSHR (0.44) | CA1CA2TSHRKDM4EMAPT | |
| SCHEMBL8404530 | 0.81 | CYP2A6 (0.52) | CA1CA2TSHRKDM4EMAPT | |
| SCHEMBL8405892 | 0.80 | TSHR (0.37) | CA1CA2TSHRKDM4EMAPT | |
| SCHEMBL12317792 | 0.80 | TSHR (0.50) | TSHRKDM4EALDH1A1 | |
| SCHEMBL10188102 | 0.78 | TSHR (0.48) | TSHRKDM4EMAPTCASP1CASP7 | |
| SCHEMBL8267880 | 0.78 | TSHR (0.54) | CA1CA2TSHRKDM4EMAPT | |
| SCHEMBL8269230 | 0.78 | GPR35 (0.46) | CA1CA2TSHRKDM4EMAPT | |
| SCHEMBL8404523 | 0.78 | GPR35 (0.46) | CA1CA2TSHRKDM4EMAPT | |
| SCHEMBL8404526 | 0.78 | CYP2A6 (0.42) | CA1CA2TSHRKDM4EMAPT | |
| SCHEMBL8404532 | 0.78 | CYP1A2 (0.42) | CA1CA2TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |