SCHEMBL8404585

SCHEMBL8404585

C=CC(O)C(O)C(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 9/20 0.41
KCNH2 Q12809 1/20 0.40
TRPA1 O75762 1/20 0.39
CA4 P22748 1/20 0.38
KMT2A Q03164 1/20 0.38
LTA4H P09960 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ACP3 P15309 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6039133 0.82 KIF11 (0.46) KIF11KCNH2TRPA1CA4LTA4H
SCHEMBL8399656 0.81 KIF11 (0.44) KIF11KCNH2TRPA1CA4KMT2A
SCHEMBL27757625 0.76 KIF11 (0.52) KIF11KCNH2LTA4HLMNAHTT
SCHEMBL8399786 0.75 KIF11 (0.43) KIF11KCNH2CA4KMT2ALTA4H
SCHEMBL15517407 0.75 KIF11 (0.56) KIF11KCNH2CA4KMT2ALTA4H
SCHEMBL8399775 0.75 CASR (0.48) KIF11KCNH2KMT2ALMNASMN1; SMN2
SCHEMBL9559237 0.74 KIF11 (0.51) KIF11KCNH2TRPA1CA4KMT2A
SCHEMBL8400095 0.74 KIF11 (0.45) KIF11KCNH2ACP3LMNA
SCHEMBL10179183 0.73 CA4 (0.50) KIF11KCNH2TRPA1CA4KMT2A
SCHEMBL10173286 0.73 CA4 (0.50) KIF11KCNH2TRPA1CA4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6008398-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-12-28 US disclosed
US-5919965-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-07-06 US disclosed
EP-0880532-A4 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1999-06-09 EP disclosed
EP-0880532-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1998-12-02 EP disclosed
EP-0804443-A4 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1998-04-29 EP disclosed
EP-0804443-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-11-05 EP disclosed
WO-1997028168-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-08-07 WO disclosed
WO-1996022297-A9 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS 1996-10-03 WO disclosed
WO-1996022297-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1996-07-25 WO disclosed