Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.63 |
| ▸ | CNR2 | P34972 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | RGS12 | O14924 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13214171 | 0.92 | CNR1 (0.65) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL14026964 | 0.81 | CNR1 (0.75) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL9701563 | 0.79 | CNR1 (0.53) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL13376363 | 0.78 | CNR1 (0.84) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL14613696 | 0.78 | CNR1 (0.84) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| Win-552122 SCHEMBL29381882 | 0.77 | CNR1 (1.00) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| Win-552122 SCHEMBL29410177 | 0.77 | CNR1 (1.00) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| Win-552122 SCHEMBL29361053 | 0.77 | CNR1 (1.00) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| Win-552122 SCHEMBL3680086 | 0.77 | CNR1 (1.00) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| Win-552122 SCHEMBL29611661 | 0.77 | CNR1 (1.00) | CNR1CNR2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763607-B2 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARMACEUTICALS GMBH (DE) | 2010-07-27 | — | — | US | disclosed |
| US-20070254862-A1 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
| US-20070191357-A1 | METHODS OF USING POTASSIUM CHANNEL INHIBITING COMPOUNDS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191357-A1 | METHODS OF USING POTASSIUM CHANNEL INHIBITING COMPOUNDS | KCNN3, KCNN1, KCNN2 | CNR1 375/4885CNR2 328/4885ALDH1A1 2776/4885 |
| US-20070254862-A1 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | CNR1, CNR2, KCNJ11 | CNR1 1/4885CNR2 2/4885ALDH1A1 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.