⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889879 | 0.76 | — | — | |
| SCHEMBL15294568 | 0.73 | — | — | |
| SCHEMBL23555364 | 0.73 | — | — | |
| SCHEMBL141187 | 0.73 | — | — | |
| SCHEMBL22525063 | 0.73 | — | — | |
| SCHEMBL15116997 | 0.70 | — | — | |
| SCHEMBL14963602 | 0.70 | — | — | |
| SCHEMBL22477584 | 0.70 | — | — | |
| SCHEMBL4763104 | 0.70 | — | — | |
| SCHEMBL13104902 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| US-11826485-B2 | Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20200231620-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2020-07-23 | — | — | US | disclosed |
| US-10023861-B2 | Oligomer-conjugate complexes and their use | IONIS PHARMACEUTICALS, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| US-9976138-B2 | Methods and compounds useful in conditions related to repeat expansion | IONIS PHARMACEUTICALS, INC. (US) | 2018-05-22 | — | — | US | disclosed |
| US-20170267681-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | MIDCAP FINANCIAL TRUST, AS AGENT | 2017-09-21 | — | — | US | disclosed |
| US-20170216272-A1 | COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-03 | — | — | US | disclosed |
| WO-2017093543-A2 | ANTI-BACTERIAL COMPOUNDS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |
| US-9629840-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2017-04-25 | — | — | US | disclosed |
| US-7186822-B2 | Process for the synthesis of oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070032620-A1 | Chemical vapor deposition of hydrogel films | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-02-08 | — | — | US | disclosed |
| US-20070020309-A1 | Safe and effective biofilm inhibitory compounds and health related uses thereof | CUTLER, ELIOT | 2007-01-25 | — | — | US | disclosed |
| US-20070021493-A1 | Mediators of hedgehog signaling pathways, compositions and uses related thereto | CURIS, INC. (US) | 2007-01-25 | — | — | US | disclosed |
| US-20070020384-A1 | Environmentally benign crop protection agents | CUTLER, ELIOT | 2007-01-25 | — | — | US | disclosed |
| US-20070015768-A1 | Ubiquitin ligase inhibitors and methods related thereto | PROTEOLOGICS, LTD. (IL) | 2007-01-18 | — | — | US | disclosed |
| US-7160732-B2 | Fluorescein-based metal sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7157429-B1 | Inhibiting the dipeptidylpeptidase proteolysis of Glucagon-like peptide, by administering a dipeptides consisting Pro-Pro, Ala-Pro, and (D)-Ala-(L)-Ala; treating metabolism disorders, diabetes, obesity, atherosclerosis | TRUSTEES OF TUFTS COLLEGE (US) | 2007-01-02 | — | — | US | disclosed |
| US-20050070578-A1 | Small organic molecule regulators of cell proliferation | CURIS, INC. | 2005-03-31 | — | — | US | disclosed |
| US-20040176307-A1 | Inhibiting dipeptidylpeptidase proteolysis of glucagon-like peptide 1 | ARISAPH PHARMACEUTICALS, INC. | 2004-09-09 | — | — | US | disclosed |