Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405219 | 1.00 | MAPT (0.36) | MAPTNPSR1L3MBTL1POLBHRH3 | |
| SCHEMBL29099778 | 0.79 | HRH3 (0.35) | MAPTHRH3CYP11B1CYP11B2RAPGEF4 | |
| SCHEMBL1610966 | 0.77 | HRH3 (0.34) | HRH3CYP11B1CYP11B2RAPGEF4HTR1D | |
| SCHEMBL900740 | 0.73 | HRH3 (0.38) | MAPTHRH3CYP11B1CYP11B2RAPGEF4 | |
| SCHEMBL22296029 | 0.73 | HRH3 (0.38) | MAPTHRH3CYP11B1CYP11B2RAPGEF4 | |
| SCHEMBL11761370 | 0.72 | MAPT (0.34) | MAPTNPSR1L3MBTL1POLB | |
| SCHEMBL327402 | 0.71 | GAA (0.40) | MAPTNPSR1POLBHRH3CYP11B1 | |
| SCHEMBL1124861 | 0.71 | HRH3 (0.36) | MAPTHRH3CYP11B1CYP11B2RAPGEF4 | |
| SCHEMBL1610022 | 0.71 | HRH3 (0.36) | MAPTHRH3CYP11B1CYP11B2RAPGEF4 | |
| SCHEMBL10563769 | 0.71 | SHBG (0.32) | MAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977419-A | Process for the preparation of substituted phenylpropenes | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0676388-B1 | Process for the preparation of phenylacetic acid derivatives and intermediate products | BAYER AG (DE) | 1999-07-14 | — | — | EP | disclosed |
| EP-0903332-A1 | Process for preparing substituted phenylpropenen | BAYER AG (DE) | 1999-03-24 | — | — | EP | disclosed |
| EP-0903332-A1 | Process for preparing substituted phenylpropenen | BAYER AG (DE) | 1999-03-24 | — | — | EP | disclosed |
| US-5756858-A | Process for the preparation of substituted phenylacetic acid derivatives and novel intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0676388-A2 | Process for the preparation of phenylacetic acid derivatives and intermediate products | BAYER AG (DE) | 1995-10-11 | — | — | EP | disclosed |