Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405322 | 0.78 | MAPT (0.52) | TP53MAPTGAAMAPK1SMN1; SMN2 | |
| SCHEMBL8572886 | 0.72 | MEN1 (0.49) | LMNATP53PDE4BOPRK1ADORA1 | |
| SCHEMBL8408363 | 0.71 | MEN1 (0.47) | LMNATP53PDE4BOPRK1ADORA1 | |
| SCHEMBL8408093 | 0.71 | ALDH1A1 (0.44) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8407040 | 0.70 | MAPT (0.64) | LMNATP53MEN1KMT2AMAPT | |
| SCHEMBL28731713 | 0.69 | ACACB (0.50) | HPGDLMNAPDE4BMEN1KMT2A | |
| SCHEMBL31141716 | 0.69 | ACACB (0.50) | HPGDLMNAPDE4BMEN1KMT2A | |
| SCHEMBL31141679 | 0.69 | ACACB (0.50) | HPGDLMNAPDE4BMEN1KMT2A | |
| SCHEMBL31493850 | 0.66 | KMT2A (0.52) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21630699 | 0.66 | KMT2A (0.52) | HPGDLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952504-A | REACTING A SULFONATED, HALOGENATED OR PHOSPHONATED 1,7-NAPHTHYRIDINE COMPOUNDS WITH AN AROMATIC AMINE DERIVATIVE; ANTIULCER AGENT | YUNGJIN PHARMACEUTICAL COMPANY, LTD. (KR) | 1999-09-14 | — | — | US | disclosed |
| WO-1997003074-A1 | 4-AMINO-3-ACYLNAPHTHYRIDINE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-01-30 | — | — | WO | disclosed |