Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155365 | 0.85 | KDM4E (0.58) | KDM4EHSD17B10MGLLTDP1PIM1 | |
| SCHEMBL31416604 | 0.85 | KDM4E (0.58) | KDM4EHSD17B10MGLLTDP1PIM1 | |
| SCHEMBL18305548 | 0.77 | KDM4E (0.58) | KDM4EHSD17B10MGLLTDP1MAOB | |
| SCHEMBL19282095 | 0.74 | MAOB (0.42) | KDM4EMAOBAPPMIFPIM1 | |
| SCHEMBL147973 | 0.74 | KDM4E (1.00) | KDM4EHSD17B10MGLLTDP1MAOB | |
| SCHEMBL4494679 | 0.73 | KDM4E (0.53) | KDM4EHSD17B10MGLLTDP1MAOB | |
| SCHEMBL12100426 | 0.73 | MGLL (0.53) | KDM4EHSD17B10MGLLTDP1MAOB | |
| SCHEMBL30417822 | 0.73 | KDM4E (0.53) | KDM4EHSD17B10MGLLTDP1MIF | |
| Naphthalene SCHEMBL29205373 | 0.72 | KDM4E (0.96) | KDM4EHSD17B10MGLLTDP1MAOB | |
| SCHEMBL21983882 | 0.71 | MAOB (0.41) | KDM4EHSD17B10MAOBAPPMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174306-B | Organic light-emitting compound and organic light-emitting device | SFC株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-108929234-B | Aromatic amine derivative and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2021-12-14 | — | — | CN | disclosed |
| US-20120129828-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. | 2012-05-24 | — | — | US | disclosed |
| US-20120129828-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. | 2012-05-24 | — | — | US | disclosed |
| WO-2009154780-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129828-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | S1PR1, S1PR5, S1PR2 | KDM4E 2854/4885HSD17B10 2249/4885MGLL 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.