SCHEMBL840561

SCHEMBL840561

Oc1ncc2nc[nH]c2n1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PARP1 P09874 1/20 0.32
TP53 P04637 1/20 0.30
PTGS1 P23219 1/20 0.30
HBB P68871 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10572250 0.98 KDM4E (0.34) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL2009845 0.78 KDM4E (0.35) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL29941283 0.75 CHEK1 (0.36) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL1721317 0.75 CHEK1 (0.36) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL1590661 0.74 KDM4E (0.35) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL2968460 0.74 KDM4E (0.35) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL5170025 0.74 KDM4E (0.35) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL22430792 0.74 KDM4E (0.35) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL11486221 0.74 KDM4E (0.35) KDM4EALDH1A1HPGDGLAGAA
2-Aminopurine SCHEMBL29901502 0.74 ALDH1A1 (0.48) KDM4EALDH1A1HPGDGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119455413-A Allopurinol desalination and evaporation device and desalination and evaporation method thereof 宜兴市星宇药业有限公司 2025-02-18 CN claimed
CN-119031915-A Methods and compositions for treating skin proliferative disorders and other skin conditions 不对称疗法有限责任公司 2024-11-26 CN claimed
WO-2023202686-A1 COMPOSITION AND METHOD FOR INHIBITING XANTHINE DEHYDROGENASE (XDH) 上海舶望制药有限公司 2023-10-26 WO claimed
CN-115968815-A Induction method for efficiently producing full-male nibea albiflora triploid 浙江省海洋水产研究所 2023-04-18 CN claimed
WO-2013181296-A2 COMPOSITIONS AND METHODS FOR MANAGING WEIGHT UNIGEN, INC. (US) 2013-12-05 WO claimed
WO-2002092072-A2 DRUGS FOR THE TREATMENT OF THE ALZHEIMER DISEASE NICOX S.A. (FR) 2002-11-21 WO claimed
EP-0741741-B1 MODIFIED OLIGONUCLEOTIDES NOVARTIS AG (CH) 2002-08-28 EP claimed
US-6066447-A INCLUDING NUCLEOSIDE DIMERS WITH MODIFIED BACKBONES; FOR VIRICIDES AND ANTISENSE AGENTS NOVARTIS CORPORATION (US) 2000-05-23 US claimed
US-6011112-A SILYLATED ORGANONITROGEN COMPOUNDS WACKER-CHEMIE GMBH (DE) 2000-01-04 US claimed
EP-0852606-B1 ORGANOPOLYSILOXANE COMPOUNDS CROSS-LINKABLE BY CLEAVING OF ALCOHOLS TO FORM ELASTOMERS WACKER CHEMIE GMBH (DE) 1999-04-14 EP claimed
WO-1995020597-A1 MODIFIED OLIGONUCLEOTIDES CIBA-GEIGY AG (CH) 1995-08-03 WO claimed
EP-0644196-A1 TTTr as a protecting group in nucleotide synthesis CIBA-GEIGY AG (CH) 1995-03-22 EP claimed
EP-0634927-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-01-25 EP claimed
US-5380521-A Method for obtaining deodorant extract from tissue culture of plants in family oleaceae MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1995-01-10 US claimed
US-5321032-A Peptide compounds and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-06-14 US claimed
EP-0577558-A2 Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates CIBA-GEIGY AG (CH) 1994-01-05 EP claimed
WO-1993017671-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA STATENS SERUMINSTITUT (DK) 1993-09-16 WO claimed
EP-0016845-B1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1983-07-13 EP claimed
US-4341868-A PEROXIDATION; COLORIMETRY; QUANTITAVE ANALYSIS; ONE-STEP; ENTEROBACTER KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-07-27 US claimed
EP-0016845-A1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1980-10-15 EP claimed