Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187211 | 0.89 | ALDH1A1 (0.46) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL188196 | 0.89 | ALDH1A1 (0.46) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL1197076 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL31275823 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL20854267 | 0.85 | ALDH1A1 (0.54) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL7078048 | 0.84 | HTR2A (0.43) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL28046868 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL4995768 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP2D6L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL15927414 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL124590 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016110237-A1 | Α-CARBOLINE COMPOUND , PREPARATION METHOD THEREFOR AND USES THEREOF | 中国科学院上海药物研究所 | 2016-07-14 | — | — | WO | disclosed |
| US-9284272-B2 | Inhibitors of histone methyltransferase G9a | ABBVIE INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20150274660-A1 | INHIBITORS OF HISTONE METHYLTRANSFERASE G9a | ABBVIE INC. | 2015-10-01 | — | — | US | disclosed |
| EP-0826669-B1 | Composition for dyeing keratin fibres containing 2-iminoindol derivatives | OREAL (FR) | 1999-06-30 | — | — | EP | disclosed |
| US-5876465-A | Compositions for dyeing keratin fibres containing 2-iminoindoline derivatives and dyeing process | L'OREAL (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0826669-A1 | Composition for dyeing keratin fibres | L'OREAL (FR) | 1998-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274660-A1 | INHIBITORS OF HISTONE METHYLTRANSFERASE G9a | EHMT1, EHMT2, EZH2 | ALDH1A1 1370/4885CYP2D6 4663/4885L3MBTL1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.