Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334191 | 0.84 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL7334195 | 0.81 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL13403230 | 0.80 | AVPR1A (0.53) | AVPR2AVPR1A | |
| SCHEMBL8562029 | 0.79 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL3553886 | 0.79 | AVPR1A (0.53) | AVPR2AVPR1A | |
| SCHEMBL3552960 | 0.79 | AVPR1A (0.63) | AVPR2AVPR1A | |
| SCHEMBL5788208 | 0.79 | AVPR1A (0.50) | AVPR2AVPR1A | |
| SCHEMBL5783972 | 0.79 | AVPR2 (0.41) | AVPR2AVPR1A | |
| SCHEMBL8318185 | 0.76 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL7333390 | 0.76 | AVPR2 (0.62) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968930-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5968937-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5516774-A | TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1996-05-14 | — | — | US | disclosed |