Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560660 | 0.87 | NPC1 (0.54) | AVPR2AVPR1A | |
| SCHEMBL8558555 | 0.85 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL8560800 | 0.84 | AVPR2 (0.79) | AVPR2AVPR1A | |
| SCHEMBL8558993 | 0.84 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL7357045 | 0.83 | AVPR2 (0.68) | AVPR2AVPR1ALMNATP53 | |
| SCHEMBL7334195 | 0.83 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL8560873 | 0.82 | ACHE (0.60) | AVPR2AVPR1A | |
| SCHEMBL7369344 | 0.82 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL8564269 | 0.82 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL8560986 | 0.82 | LMNA (0.56) | AVPR2AVPR1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |