Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296585 | 1.00 | NPY5R (0.44) | NPY5RKLK7LMNATDP1ADRB2 | |
| SCHEMBL8405959 | 1.00 | NPY5R (0.44) | NPY5RKLK7LMNATDP1ADRB2 | |
| SCHEMBL8405110 | 0.90 | NPY5R (0.45) | NPY5RKLK7LMNATDP1ADRB2 | |
| SCHEMBL8405788 | 0.89 | CNR2 (0.46) | KLK7LMNATDP1ADRB2ADRB1 | |
| SCHEMBL8405974 | 0.88 | PPARG (0.44) | KLK7LMNATDP1ADRB2ADRB1 | |
| SCHEMBL8406235 | 0.88 | ADRB2 (0.39) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL8402266 | 0.88 | PPARG (0.41) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL8402071 | 0.87 | ADRB2 (0.51) | ADRB2ADRB1ADRA1DADRA1AADRA1B | |
| SCHEMBL8405100 | 0.87 | MAPT (0.41) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL8405122 | 0.87 | MAOB (0.41) | KLK7LMNATDP1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977374-A | 5-(4-hydroxy-OR 4-acetoxy-benzyl)-3- triphenylmethylthiazolidine-2,4-dione and method for producing same | SANKYO COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |