SCHEMBL8406643

SCHEMBL8406643

CCCNc1oncc1C1=CCCN(C)C1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 6/20 0.44
CHRM3 P20309 6/20 0.44
CHRM4 P08173 5/20 0.44
CHRM5 P08912 5/20 0.44
CHRM1 P11229 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL7477838 0.93 CHRM2 (0.50) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL8406017 0.93 CHRM2 (0.46) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL8402127 0.91 CHRM1 (0.46) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL8401818 0.90 CHRM1 (0.48) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL7419072 0.90 CHRM2 (0.46) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL8405871 0.86 CHRM2 (0.52) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL8401885 0.85 CHRM2 (0.53) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL8404876 0.85 CHRM1 (0.39) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL8405801 0.85 CHRM2 (0.53) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL8404872 0.84 CHRM1 (0.41) CHRM2CHRM3CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994373-A COGNITION ACTIVATORS; GASTROINTESTINAL DISORDERS; PSYCHOLOGICAL DISORDERS NOVO NORDISK A/S NOVO ALLE DK 2880 (DK) 1999-11-30 US claimed