Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7424487 | 0.93 | CHRM2 (0.52) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8406643 | 0.90 | CHRM2 (0.44) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8406017 | 0.87 | CHRM2 (0.46) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8402127 | 0.86 | CHRM1 (0.46) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8404872 | 0.86 | CHRM1 (0.41) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8401818 | 0.85 | CHRM1 (0.48) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8405398 | 0.85 | CHRM2 (0.43) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL7477838 | 0.83 | CHRM2 (0.50) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8404876 | 0.83 | CHRM1 (0.39) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL8401770 | 0.83 | CHRNB4 (0.41) | CHRM2CHRM3CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994373-A | COGNITION ACTIVATORS; GASTROINTESTINAL DISORDERS; PSYCHOLOGICAL DISORDERS | NOVO NORDISK A/S NOVO ALLE DK 2880 (DK) | 1999-11-30 | — | — | US | claimed |
| EP-0835255-A1 | NOVEL SUBSTITUTED AZACYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-15 | — | — | EP | claimed |
| WO-1997001555-A1 | NOVEL SUBSTITUTED AZACYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-01-16 | — | — | WO | claimed |