Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354322 | 0.75 | GABRA1 (0.48) | EEDKCNH2HTR2AHTR2C | |
| SCHEMBL2610674 | 0.75 | GABRA1 (0.46) | EEDKCNH2HTR2AHTR2C | |
| SCHEMBL16815738 | 0.72 | CYP1A2 (0.44) | EEDHTR2AHTR2CCYP1A2KMT2A | |
| SCHEMBL5988407 | 0.72 | HTR2A (0.44) | EEDHTR2AHTR2C | |
| SCHEMBL30684489 | 0.72 | HTR2A (0.44) | EEDHTR2AHTR2C | |
| SCHEMBL8402802 | 0.72 | MEN1 (0.35) | MEN1NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3794977 | 0.72 | EED (0.43) | EEDKCNH2HTR2AHTR2C | |
| SCHEMBL8406962 | 0.72 | MEN1 (0.33) | MEN1NPC1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL5986131 | 0.71 | HTR2A (0.43) | HTR2AHTR2C | |
| SCHEMBL6679464 | 0.71 | EED (0.45) | EEDKCNH2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923567-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008834-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1998-03-05 | — | — | WO | disclosed |