Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995772 | 0.83 | NOS2 (0.47) | HRH3NOS2RAPGEF4MAPTALDH1A1 | |
| SCHEMBL113792 | 0.81 | NOS2 (0.37) | HRH3NOS2RAPGEF4MAPTALDH1A1 | |
| SCHEMBL8388464 | 0.77 | NOS2 (0.42) | HRH3NOS2RAPGEF4MAPTALDH1A1 | |
| SCHEMBL13021414 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13021415 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5696488 | 0.73 | AKT1 (0.36) | HRH3NOS2MAPTALDH1A1KDM4E | |
| SCHEMBL17669771 | 0.72 | SLC6A2 (0.33) | HRH3CYP11B1CYP11B2SLC6A2SLC6A4 | |
| SCHEMBL12471861 | 0.72 | XIAP (0.35) | MAPTALDH1A1KDM4ELMNANR3C1 | |
| Hydrochloric Acid SCHEMBL31545415 | 0.71 | — | — | |
| SCHEMBL95192 | 0.70 | HRH3 (0.40) | HRH3RAPGEF4MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977419-A | Process for the preparation of substituted phenylpropenes | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0676388-B1 | Process for the preparation of phenylacetic acid derivatives and intermediate products | BAYER AG (DE) | 1999-07-14 | — | — | EP | disclosed |
| EP-0903332-A1 | Process for preparing substituted phenylpropenen | BAYER AG (DE) | 1999-03-24 | — | — | EP | disclosed |
| EP-0903332-A1 | Process for preparing substituted phenylpropenen | BAYER AG (DE) | 1999-03-24 | — | — | EP | disclosed |
| US-5756858-A | Process for the preparation of substituted phenylacetic acid derivatives and novel intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0676388-A2 | Process for the preparation of phenylacetic acid derivatives and intermediate products | BAYER AG (DE) | 1995-10-11 | — | — | EP | disclosed |