SCHEMBL8407296

SCHEMBL8407296

CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCCl

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.40
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8659755 0.96 HTT (0.40) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8406003 0.92 HTT (0.37) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8408644 0.92 HTT (0.37) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8408496 0.90 HTT (0.40) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8564449 0.89 HTT (0.39) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8408736 0.89 HTT (0.39) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL7627660 0.89 HTT (0.39) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8022028 0.89 HTT (0.39) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8405371 0.88 HTT (0.36) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8408548 0.88 HTT (0.36) HTTKDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed