SCHEMBL8564449

SCHEMBL8564449

CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCCO

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
THRA P10827 2/20 0.31
THRB P10828 2/20 0.31
PLA2G2A P14555 1/20 0.31
TP53 P04637 1/20 0.30
MAPK1 P28482 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8408496 0.96 HTT (0.40) HTTL3MBTL1KDM4EALDH1A1GAA
SCHEMBL8408512 0.92 HTT (0.36) HTTL3MBTL1KDM4EALDH1A1GAA
SCHEMBL8408696 0.92 HTT (0.36) HTTL3MBTL1KDM4EALDH1A1THRB
SCHEMBL8659755 0.90 HTT (0.40) HTTL3MBTL1KDM4EALDH1A1GAA
SCHEMBL7627660 0.89 HTT (0.39) HTTL3MBTL1KDM4EALDH1A1GAA
SCHEMBL8407296 0.89 HTT (0.40) HTTL3MBTL1KDM4EALDH1A1GAA
SCHEMBL8405799 0.88 HTT (0.36) HTTL3MBTL1KDM4EALDH1A1GAA
SCHEMBL8409335 0.88 HTT (0.36) HTTKDM4EALDH1A1GAAMAPT
SCHEMBL8011722 0.88 HTT (0.38) HTTL3MBTL1KDM4EALDH1A1GAA
SCHEMBL7631862 0.88 HTT (0.38) HTTL3MBTL1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed