Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961679 | 0.89 | CA1 (0.64) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL14452650 | 0.78 | CA2 (0.57) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL10335075 | 0.77 | CA1 (0.55) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL240515 | 0.77 | CA2 (0.80) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL29602570 | 0.77 | CA2 (0.80) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL22360314 | 0.75 | CA1 (0.64) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL18715652 | 0.75 | CA2 (0.64) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL12355670 | 0.74 | CA1 (0.52) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL22152324 | 0.73 | CA1 (0.61) | CA1CA2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL39130 | 0.73 | CA2 (1.00) | CA1CA2ALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905055-A | TUNGSTEN, RHENIUM, OR MOLYBDENUM COMPOUNDS ATTACHED TO CATALYST SUPPORT; NIOBIUM COMPOUND PROMOTER; LOW TEMPERATURE ACTIVITY | DSM N.V. (NL) | 1999-05-18 | — | — | US | disclosed |
| EP-0758267-B1 | HETEROGENEOUS METATHESIS CATALYST | DSM NV (NL) | 1998-03-18 | — | — | EP | disclosed |