SCHEMBL840779

SCHEMBL840779

C=CC(=O)OCCC[Si](C)(Cl)Cl

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 1/20 0.58
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HCAR2 Q8TDS4 3/20 0.34
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9805388 0.95 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29965323 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL31679615 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL31679617 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7523332 0.91 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL691353 0.89 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9805672 0.89 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8589230 0.85 TSHR (0.44) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26187833 0.85 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL308812 0.85 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391819-B2 Fluoropolymer-based hybrid organic/inorganic composites SYENSQO SA (BE) 2025-08-19 US claimed
EP-3724939-B1 FLUOROPOLYMER MEMBRANE FOR ELECTROCHEMICAL DEVICES SYENSQO SA (BE) 2025-08-13 EP claimed
CN-118955916-B Cationic etherifying agent and preparation method thereof 东营市泽澳化工有限责任公司 2025-01-10 CN claimed
CN-118955916-A Cationic etherifying agent and preparation method thereof 东营市泽澳化工有限责任公司 2024-11-15 CN claimed
WO-2024172770-A1 PRINTABLE WAX, METHOD OF PRINTING, AND METHOD FOR FLOW VISCOSITY CONTROL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2024-08-22 WO claimed
CN-111466042-B Fluoropolymer membranes for electrochemical devices 索尔维公司 2024-03-29 CN claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
CN-116903259-A Hybrid organic/inorganic composite materials based on fluoropolymers 索尔维特殊聚合物意大利有限公司 2023-10-20 CN claimed
CN-116804067-A Polymer electrolyte, preparation method thereof and lithium metal battery 北京车和家信息技术有限公司 2023-09-26 CN claimed
US-11702491-B2 Membrane including fluoropolymer hybrid organic/inorganic composite, and electrochemical device having the same SOLVAY SA (BE) 2023-07-18 US claimed
EP-0593297-A1 Resin composition for coating and paint HITACHI CHEMICAL CO., LTD. (JP) 1994-04-20 EP claimed
EP-0495936-A4 METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER 1993-03-17 EP claimed
WO-1992021579-A1 MOISTURE RESISTANT GLASS CONTAINER ADVANCED GLASS TREATMENT SYSTEMS (US) 1992-12-10 WO claimed
WO-1992021492-A1 MOISTURE RESISTANT GLASS ARTICLE ADVANCED GLASS TREATMENT SYSTEMS (US) 1992-12-10 WO claimed
EP-0495936-A1 METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER ADVANCED GLASS TREATMENT SYSTEMS (US) 1992-07-29 EP claimed
WO-1991019606-A1 METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER ADVANCED GLASS TREATMENT SYSTEMS (US) 1991-12-26 WO claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed
EP-0311348-A2 Novel macromers containing a polyether moiety, process of preparing them and polymers thereof Nippon Oil Co., Ltd. (JP) 1989-04-12 EP claimed
EP-0208972-A2 Polysilane-siloxane oligomers and copolymers and methods of making the same HÜLS AMERICA INC. (a Delaware corporation) (US) 1987-01-21 EP claimed
US-4626583-A Polysilane-siloxane oligomers and copolymers and methods of making the same PETRARCH SYSTEMS INC. (US) 1986-12-02 US claimed