SCHEMBL840780

SCHEMBL840780

C=CC(=O)OCCCC[SiH](Cl)Cl

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.67
ALDH1A1 P00352 4/20 0.67
CYP3A4 P08684 2/20 0.67
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATM Q13315 1/20 0.35
HCAR2 Q8TDS4 3/20 0.34
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30418050 0.98 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30417430 0.98 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9805399 0.98 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL691866 0.94 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16253926 0.86 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL244114 0.83 TSHR (0.95) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3628946 0.82 TSHR (0.69) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9101988 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8493780 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL13945622 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391819-B2 Fluoropolymer-based hybrid organic/inorganic composites SYENSQO SA (BE) 2025-08-19 US claimed
EP-3724939-B1 FLUOROPOLYMER MEMBRANE FOR ELECTROCHEMICAL DEVICES SYENSQO SA (BE) 2025-08-13 EP claimed
CN-116804067-A Polymer electrolyte, preparation method thereof and lithium metal battery 北京车和家信息技术有限公司 2023-09-26 CN claimed
US-11702491-B2 Membrane including fluoropolymer hybrid organic/inorganic composite, and electrochemical device having the same SOLVAY SA (BE) 2023-07-18 US claimed
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
CN-113956727-B Colorant composition and coated article 广东华润涂料有限公司 2023-02-17 CN claimed
EP-3724140-B1 FLUOROPOLYMER-BASED HYBRID ORGANIC/INORGANIC COMPOSITES SOLVAY SPECIALTY POLYMERS IT (IT) 2022-03-09 EP claimed
CN-113956727-A Colorant composition and coated article 广东华润涂料有限公司 2022-01-21 CN claimed
US-11092574-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2021-08-17 US claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
EP-1451554-A1 HYDROPHOBIC SURFACE CHIP Ciphergen Biosystems, Inc. (US) 2004-09-01 EP claimed
US-20030218130-A1 Biochips with surfaces coated with polysaccharide-based hydrogels CIPHERGEN BIOSYSTEMS, INC. 2003-11-27 US claimed
WO-2003093785-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS CIPHERGEN BIOSYSTEMS, INC. (US) 2003-11-13 WO claimed
WO-2003079402-A2 LATEX BASED ADSORBENT CHIP CIPHERGEN BIOSYSTEMS, INC. (US) 2003-09-25 WO claimed
US-20030124371-A1 Hydrophobic surface chip CIPHERGEN BIOSYSTEMS, INC. 2003-07-03 US claimed
WO-2003040700-A1 HYDROPHOBIC SURFACE CHIP CIPHERGEN BIOSYSTEMS, INC. (US) 2003-05-15 WO claimed
US-20030032043-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-02-13 US claimed
US-20030017464-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-01-23 US claimed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
EP-0311348-A2 Novel macromers containing a polyether moiety, process of preparing them and polymers thereof Nippon Oil Co., Ltd. (JP) 1989-04-12 EP claimed