Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942660 | 0.93 | ALDH1A1 (0.54) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL8410571 | 0.91 | HTT (0.51) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL8410860 | 0.90 | HTT (0.50) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL29757307 | 0.89 | CYP2C19 (0.59) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL16207718 | 0.89 | CYP2C19 (0.59) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL7942593 | 0.86 | HIF1A (0.55) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL8409819 | 0.86 | CYP2C19 (0.53) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL6057732 | 0.85 | CYP2C19 (0.49) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL7941092 | 0.85 | CYP2C19 (0.49) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL8411161 | 0.84 | ALDH1A1 (0.62) | HTTALDH1A1MAPK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874494-A | DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |