Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.82 |
| ▸ | HPGD | P15428 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.82 |
| ▸ | HTT | P42858 | 2/20 | 0.82 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942343 | 0.93 | ALDH1A1 (0.70) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8409980 | 0.91 | ALDH1A1 (0.68) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| Ambunol SCHEMBL5991371 | 0.90 | ALDH1A1 (1.00) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8411087 | 0.90 | ALDH1A1 (0.66) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9416994 | 0.89 | ALDH1A1 (0.63) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9416933 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7944793 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9475308 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7941185 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7944772 | 0.83 | ALDH1A1 (0.84) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874494-A | DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |