Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234178 | 0.88 | TSHR (0.47) | EGFRALOX15TSHRTHRB | |
| SCHEMBL11433928 | 0.86 | EGFR (0.36) | EGFRALOX15TSHR | |
| SCHEMBL30369121 | 0.82 | EGFR (0.36) | EGFRALOX15 | |
| SCHEMBL9087682 | 0.81 | EGFR (0.40) | EGFRALOX15CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL3289278 | 0.79 | EGFR (0.41) | EGFRALOX15CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL113147 | 0.79 | ALOX15 (0.53) | EGFRALOX15TSHRCHRNB2CHRNA4 | |
| SCHEMBL5932536 | 0.79 | EGFR (0.39) | EGFRALOX15CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5933627 | 0.79 | EGFR (0.39) | EGFRALOX15CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5932523 | 0.79 | EGFR (0.39) | EGFRALOX15CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5836238 | 0.78 | EGFR (0.38) | EGFRALOX15CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663206-B1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | KAO CORP (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0663206-A1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | Kao Corporation (JP) | 1995-07-19 | — | — | EP | disclosed |