Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 11/20 | 0.41 |
| ▸ | CDC25B | P30305 | 10/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152194 | 1.00 | USP2 (0.42) | USP2PLA2G1BINPP5DCDC25ACDC25B | |
| SCHEMBL16152196 | 0.81 | PLA2G1B (0.55) | USP2PLA2G1BINPP5DCDC25ACDC25B | |
| SCHEMBL8408231 | 0.81 | PLA2G1B (0.55) | USP2PLA2G1BINPP5DCDC25ACDC25B | |
| SCHEMBL30653161 | 0.81 | PLA2G1B (0.55) | USP2PLA2G1BINPP5DCDC25ACDC25B | |
| SCHEMBL5335972 | 0.67 | USP2 (0.53) | USP2CDC25ACDC25BSRD5A1SRD5A2 | |
| SCHEMBL3042515 | 0.65 | NPC1L1 (0.62) | USP2INPP5DSRD5A1SRD5A2 | |
| SCHEMBL3042519 | 0.65 | NPC1L1 (0.62) | USP2INPP5DSRD5A1SRD5A2 | |
| SCHEMBL3042923 | 0.65 | NPC1L1 (0.62) | USP2INPP5DSRD5A1SRD5A2 | |
| SCHEMBL10262303 | 0.65 | CDC25A (0.41) | USP2PLA2G1BINPP5DCDC25ACDC25B | |
| SCHEMBL10292137 | 0.65 | CDC25A (0.41) | USP2PLA2G1BINPP5DCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853194-B2 | Sterol derivatives and their synthesis and use | Chen, Dagang (CN) | 2014-10-07 | — | — | US | disclosed |
| US-20120130067-A1 | Sterol Derivatives and Their Synthesis and Use | Chen, Dagang (CN) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130067-A1 | Sterol Derivatives and Their Synthesis and Use | LSS, NR1H3, CYP46A1 | USP2 4284/4885PLA2G1B 1523/4885INPP5D 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.