Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405681 | 0.86 | FFAR4 (0.37) | TSHRMAPK1ALDH1A1HSD17B10TRPV1 | |
| SCHEMBL8407711 | 0.83 | FFAR4 (0.37) | TSHRALDH1A1HSD17B10CYP3A4KCNH2 | |
| SCHEMBL8409166 | 0.82 | ESR1 (0.43) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL8658023 | 0.78 | TDP1 (0.58) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL8405870 | 0.78 | CETP (0.39) | — | |
| SCHEMBL8405614 | 0.77 | FFAR4 (0.47) | CYP3A4KCNH2CACNA1CSCN5AFFAR4 | |
| SCHEMBL7073022 | 0.76 | L3MBTL1 (0.51) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL8657702 | 0.76 | TDP1 (0.63) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL8408597 | 0.75 | CETP (0.39) | — | |
| SCHEMBL8408253 | 0.75 | HRH3 (0.51) | TSHRESR1MAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |