Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.47 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405841 | 0.89 | AVPR2 (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL8406610 | 0.88 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL8406431 | 0.85 | AVPR2 (0.63) | AVPR2AVPR1AOXTR | |
| SCHEMBL8409710 | 0.77 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL8408008 | 0.76 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL5739209 | 0.75 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL8407921 | 0.74 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL7342127 | 0.73 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL8408171 | 0.69 | AVPR2 (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL9060789 | 0.67 | AVPR2 (0.53) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968930-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | claimed |
| US-5968930-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5968937-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |