Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8695811 | 0.86 | ALOX5 (0.51) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| SCHEMBL8698136 | 0.86 | ALOX5 (0.56) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| Cadaverine Tartrate SCHEMBL8700671 | 0.85 | ALOX5 (0.51) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8701005 | 0.85 | ALOX5 (0.51) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| SCHEMBL8702203 | 0.85 | ALOX5 (0.57) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8695817 | 0.85 | ALOX5 (0.55) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8697235 | 0.84 | ALOX5 (0.56) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8695889 | 0.83 | ALOX5 (0.51) | ALOX5NR3C2GRM5MCHR1CYP3A4 | |
| SCHEMBL8410986 | 0.82 | S1PR5 (0.41) | S1PR5 | |
| SCHEMBL8696026 | 0.81 | ALOX5 (0.48) | ALOX5NR3C2GRM5MCHR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |