SCHEMBL8409281

SCHEMBL8409281

Oc1cc(Cl)c(OCCCc2cccc(F)c2)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
SCN8A Q9UQD0 1/20 0.42
IDO1 P14902 2/20 0.41
AGXT P21549 2/20 0.41
SLC6A4 P31645 2/20 0.41
DRD2 P14416 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MAOB P27338 4/20 0.40
HTR2B P41595 2/20 0.39
NR4A2 P43354 1/20 0.39
DAO P14920 1/20 0.39
HTR2C P28335 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8407967 0.96 TAAR1 (0.41) TAAR1SCN8AIDO1AGXTSLC6A4
SCHEMBL8409072 0.93 HTR2C (0.44) TAAR1SCN8AIDO1AGXTSLC6A4
SCHEMBL8408784 0.85 HTR3E (0.46) TAAR1IDO1AGXTMAOBHTR2B
SCHEMBL8405810 0.85 MAOB (0.50) IDO1AGXTMAOBNR4A2
SCHEMBL8408940 0.84 SLC5A1 (0.41) SLC6A4MAOBHTR2BHTR2C
SCHEMBL8408825 0.83 IDO1 (0.46) IDO1
SCHEMBL8408837 0.83 ESR1 (0.44) TAAR1IDO1AGXTMAOB
SCHEMBL8408535 0.82 TAAR1 (0.47) TAAR1SCN8AIDO1MAOBHTR2B
SCHEMBL8407327 0.80 CNR1 (0.45) DAO
SCHEMBL8655990 0.80 SCN8A (0.36) TAAR1SCN8ASLC6A4DRD2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed