SCHEMBL8409303

SCHEMBL8409303

CCOS(=O)(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HSD11B1 P28845 1/20 0.43
SLC22A12 Q96S37 12/20 0.43
ALDH1A1 P00352 2/20 0.41
RXFP1 Q9HBX9 1/20 0.40
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6115152 0.86 MEN1 (0.50) MEN1KMT2AHSD11B1SLC22A12ALDH1A1
SCHEMBL29449482 0.86 MEN1 (0.50) MEN1KMT2AHSD11B1SLC22A12ALDH1A1
SCHEMBL8734727 0.82 MEN1 (0.39) MEN1KMT2AHSD11B1SLC22A12ALDH1A1
SCHEMBL28044850 0.82 MEN1 (0.41) MEN1KMT2AHSD11B1
SCHEMBL8763795 0.81 KMT2A (0.38) MEN1KMT2AHSD11B1SLC22A12ALDH1A1
SCHEMBL29415266 0.81 GAA (0.39) MEN1KMT2AALDH1A1
SCHEMBL778991 0.81 GAA (0.39) MEN1KMT2AALDH1A1
SCHEMBL15000825 0.81 MEN1 (0.43) MEN1KMT2AHSD11B1SLC22A12RXFP1
SCHEMBL8763833 0.80 KMT2A (0.38) MEN1KMT2AHSD11B1SLC22A12ALDH1A1
SCHEMBL13290746 0.80 KMT2A (0.51) MEN1KMT2AHSD11B1SLC22A12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115701423-A Preparation method of trifluoroethyl sulfide (sulfoxide) substituted benzene compound and intermediate thereof 沈阳化工大学 2023-02-10 CN claimed
CN-116848088-A Sulfur ether (sulfoxide) -substituted biphenyl compound and application thereof 沈阳化工大学 2023-10-03 CN disclosed
EP-3276735-B1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY BATTERY AND SODIUM SECONDARY BATTERY SUMITOMO CHEMICAL CO (JP) 2023-07-12 EP disclosed
CN-115701423-A Preparation method of trifluoroethyl sulfide (sulfoxide) substituted benzene compound and intermediate thereof 沈阳化工大学 2023-02-10 CN disclosed
CN-107431246-B Nonaqueous electrolyte for sodium secondary battery and sodium secondary battery 住友化学株式会社 2021-03-09 CN disclosed
US-20180123170-A1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY BATTERY AND SODIUM SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-03 US disclosed
EP-3276735-A1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY CELL, AND SODIUM SECONDARY CELL Sumitomo Chemical Company, Ltd. (JP) 2018-01-31 EP disclosed
CN-107431246-A Sodium rechargeable battery nonaqueous electrolytic solution and sodium rechargeable battery 住友化学株式会社 2017-12-01 CN disclosed
CN-1339432-A Extracting method for substituted phenyl compounds ROHM & HAAS (US) 2002-03-13 CN disclosed
CN-1070175-C Process for the preparation of 2, 6-disubstituted benzenesulfonates or 2, 6-disubstituted benzenesulfonates further substituted in the 3-, 4-or 5-position ROHM & HAAS (US) 2001-08-29 CN disclosed
EP-0708087-B1 Method for making a substituted benzene compound ROHM & HAAS (US) 1999-07-28 EP disclosed
CN-1174189-A Process for preparing substituted benzene compounds ROHM & HAAS (US) 1998-02-25 CN disclosed
US-5670691-A REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE ROHM AND HAAS COMPANY (US) 1997-09-23 US disclosed
EP-0708087-A1 Method for making a substituted benzene compound ROHM AND HAAS COMPANY (US) 1996-04-24 EP disclosed