SCHEMBL8734727

SCHEMBL8734727

CCOP(=O)(COS(=O)(=O)c1ccccc1C(F)(F)F)OCC

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD11B1 P28845 1/20 0.36
SLC22A12 Q96S37 8/20 0.36
F2 P00734 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
KAT6A Q92794 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8729950 0.90 MEN1 (0.35) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8730123 0.90 ALDH1A1 (0.37) HSD11B1ALDH1A1TSHR
SCHEMBL8763795 0.88 KMT2A (0.38) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8763833 0.87 KMT2A (0.38) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8729956 0.83 HSD11B1 (0.35) MEN1KMT2AHSD11B1TSHR
SCHEMBL8732823 0.83 MEN1 (0.38) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8409303 0.82 MEN1 (0.47) MEN1KMT2AHSD11B1SLC22A12ALDH1A1
SCHEMBL8763898 0.81 RAB9A (0.41) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8732679 0.81 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL8764636 0.81 KMT2A (0.41) MEN1KMT2AHSD11B1SLC22A12F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed