Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146063 | 0.74 | GLA (0.37) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL15636224 | 0.74 | — | — | |
| SCHEMBL14306611 | 0.72 | GLA (0.36) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL588865 | 0.72 | GLA (0.36) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL584895 | 0.72 | BACE1 (0.38) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL27575442 | 0.72 | BACE1 (0.38) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL8163132 | 0.70 | GLA (0.47) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL12040077 | 0.69 | BACE1 (0.36) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL623278 | 0.69 | PTPN1 (0.39) | GLANPSR1BACE1TSHRPTPN1 | |
| SCHEMBL13502650 | 0.69 | GLA (0.34) | GLANPSR1BACE1TSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | claimed |
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5739376-A | Fullerene derivatives, methods of preparing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0695287-B1 | FULLERENE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AG (DE) | 1997-10-29 | — | — | EP | disclosed |
| EP-0695287-A1 | FULLERENE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994025424-A1 | FULLERENE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |