Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.43 |
| ▸ | PGR | P06401 | 9/20 | 0.43 |
| ▸ | AR | P10275 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407081 | 0.87 | CYP19A1 (0.56) | CYP19A1NR3C1PGRARCYP3A4 | |
| SCHEMBL8407238 | 0.80 | PGR (0.62) | CYP19A1NR3C1PGRARCYP3A4 | |
| SCHEMBL23381659 | 0.79 | PGR (0.62) | CYP19A1NR3C1PGRARCYP3A4 | |
| SCHEMBL8407060 | 0.77 | SRD5A2 (0.38) | CYP19A1CYP3A4KDM4EAKR1C3LMNA | |
| SCHEMBL9174030 | 0.77 | MAPT (0.42) | CYP19A1CYP3A4KDM4EAKR1C3LMNA | |
| SCHEMBL8948940 | 0.75 | AKR1C3 (0.38) | CYP19A1CYP3A4KDM4EAKR1C3LMNA | |
| SCHEMBL12902157 | 0.75 | CYP19A1 (0.64) | CYP19A1PGRLMNASMN1; SMN2 | |
| SCHEMBL908750 | 0.75 | CYP19A1 (0.64) | CYP19A1PGRLMNASMN1; SMN2 | |
| SCHEMBL6843517 | 0.74 | CYP19A1 (0.65) | CYP19A1PGRLMNASMN1; SMN2 | |
| SCHEMBL14946858 | 0.74 | CYP19A1 (0.65) | CYP19A1PGRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |