Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 17/20 | 0.55 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408304 | 0.99 | KCNH2 (0.62) | KCNH2F10DHODH | |
| SCHEMBL8406118 | 0.97 | KCNH2 (0.60) | KCNH2F10DHODH | |
| SCHEMBL8406119 | 0.88 | F10 (0.72) | KCNH2F10 | |
| SCHEMBL8165979 | 0.88 | F10 (0.63) | KCNH2F10 | |
| SCHEMBL8408129 | 0.87 | F10 (0.72) | KCNH2F10 | |
| SCHEMBL8167211 | 0.87 | F10 (0.62) | KCNH2F10 | |
| SCHEMBL8159704 | 0.87 | KCNH2 (0.58) | KCNH2F10 | |
| SCHEMBL8171351 | 0.86 | KCNH2 (0.59) | KCNH2F10 | |
| SCHEMBL8404493 | 0.86 | F10 (0.72) | KCNH2F10 | |
| SCHEMBL8166003 | 0.85 | F10 (0.60) | KCNH2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |