SCHEMBL8409865

SCHEMBL8409865

CC1=C([Zr](C2=C(C)C=C(c3ccccc3)C2)=[Si](C)C)CC(c2ccccc2)=C1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HPGD P15428 1/20 0.31
CFTR P13569 1/20 0.31
GOPC Q9HD26 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14717692 0.81
Hydrochloric Acid SCHEMBL5702858 0.75 NPC1 (0.32) NPC1RAB9AHPGD
SCHEMBL6554391 0.71 TSHR (0.42)
SCHEMBL27898814 0.68 NPC1 (0.37) NPC1RAB9AHPGDCFTRGOPC
SCHEMBL27394159 0.68 CFTR (0.40) NPC1RAB9AHPGDCFTRGOPC
SCHEMBL27546185 0.68 ALDH1A1 (0.40) NPC1RAB9AHPGDCFTRGOPC
Hydrochloric Acid SCHEMBL7936767 0.68 NPC1 (0.32) NPC1RAB9AHPGD
SCHEMBL27519772 0.67 NPC1 (0.36) NPC1RAB9AHPGDCFTRGOPC
Hydrochloric Acid SCHEMBL8613341 0.67 NPC1 (0.36) NPC1RAB9AHPGDCFTRGOPC
Hydrochloric Acid SCHEMBL27522612 0.67 HPGD (0.38) NPC1RAB9AHPGDCFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11279189-A None JP disclosed
JP-H11279189-A METALLOCENE COMPOUND HAVING BIS(2-SUBSTITUTED-4-PHENYL-CYCLOPENTADIENYL) LIGAND, AND ITS PRODUCTION CHISSO CORP 1999-10-12 JP disclosed