Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 15/20 | 0.37 |
| ▸ | AR | P10275 | 13/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 11/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410075 | 1.00 | PGR (0.37) | PGRARNR3C1CYP3A4NR3C2 | |
| SCHEMBL8407038 | 0.88 | PGR (0.36) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8409808 | 0.88 | PGR (0.36) | PGRARNR3C1CYP3A4 | |
| SCHEMBL9019835 | 0.87 | PGR (0.49) | PGRARNR3C1CYP3A4NR3C2 | |
| SCHEMBL8409853 | 0.87 | PGR (0.36) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8407400 | 0.87 | PGR (0.36) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8407082 | 0.86 | PGR (0.42) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8407055 | 0.86 | PGR (0.42) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8407121 | 0.86 | PGR (0.39) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8409944 | 0.86 | PGR (0.39) | PGRARNR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | claimed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |