Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199100 | 0.84 | AAK1 (0.50) | AAK1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL28269131 | 0.82 | AAK1 (0.51) | AAK1TBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL1883501 | 0.81 | AAK1 (0.52) | AAK1TBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL11116083 | 0.80 | AAK1 (0.51) | AAK1TBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL11118461 | 0.80 | AAK1 (0.51) | AAK1TBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL28269146 | 0.79 | AAK1 (0.53) | AAK1TBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL14493754 | 0.79 | AAK1 (0.54) | AAK1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL28269214 | 0.78 | AAK1 (0.65) | AAK1TBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL12572858 | 0.77 | AAK1 (0.44) | AAK1TBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL28269144 | 0.77 | AAK1 (0.67) | AAK1TBXAS1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810989-B1 | NOVELLY SUBSTITUTED DTPA DERIVATIVES, METAL COMPLEXES THEREOF, PHARMACEUTICALS CONTAINING THESE COMPLEXES, DIAGNOSTIC AND THERAPEUTIC USES THEREOF AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AG (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0810989-A1 | NOVELLY SUBSTITUTED DTPA DERIVATIVES, METAL COMPLEXES THEREOF, PHARMACEUTICALS CONTAINING THESE COMPLEXES, DIAGNOSTIC AND THERAPEUTIC USES THEREOF AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996026180-A1 | NOVELLY SUBSTITUTED DTPA DERIVATIVES, METAL COMPLEXES THEREOF, PHARMACEUTICALS CONTAINING THESE COMPLEXES, DIAGNOSTIC AND THERAPEUTIC USES THEREOF AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-29 | — | — | WO | disclosed |