Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 3/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381080 | 1.00 | DNM1 (0.42) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL5397414 | 1.00 | DNM1 (0.42) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL317338 | 1.00 | DNM1 (0.42) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL5384597 | 1.00 | DNM1 (0.42) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL130956 | 1.00 | DNM1 (0.42) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL21084357 | 0.97 | DNM1 (0.40) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL21065751 | 0.97 | DNM1 (0.40) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL128657 | 0.97 | KDM5A (0.38) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL21065780 | 0.95 | KDM5A (0.37) | DNM1KDM5APHF8KDM4CKCNH2 | |
| SCHEMBL5393795 | 0.95 | DNM1 (0.48) | DNM1KDM5APHF8KDM4CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962453-A | HEPATITIS THERAPY | NIPPON SHINYAKU CO. LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0775487-A1 | TRIAZINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-05-28 | — | — | EP | disclosed |