Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129618 | 0.83 | GPR119 (0.60) | GPR119GRM1GRM5POLBSMARCA2 | |
| SCHEMBL20129601 | 0.83 | GPR119 (0.60) | GPR119GRM1GRM5POLBSMARCA2 | |
| SCHEMBL20142792 | 0.83 | GPR119 (0.60) | GPR119GRM1GRM5POLBSMARCA2 | |
| SCHEMBL4826169 | 0.82 | GPR119 (0.58) | GPR119GRM1GRM5POLBCKS1B | |
| SCHEMBL21360322 | 0.81 | GPR119 (0.56) | GPR119GRM1GRM5POLBCKS1B | |
| SCHEMBL8917888 | 0.80 | GPR119 (0.55) | GPR119GRM1GRM5POLBCKS1B | |
| SCHEMBL8916055 | 0.79 | GPR119 (0.54) | GPR119GRM1GRM5POLBUSP30 | |
| SCHEMBL8916072 | 0.78 | GPR119 (0.52) | GPR119GRM1GRM5POLBCKS1B | |
| SCHEMBL8916797 | 0.78 | GPR119 (0.52) | GPR119GRM1GRM5POLBCKS1B | |
| SCHEMBL8915717 | 0.78 | GPR119 (0.51) | GPR119GRM1GRM5POLBCKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866589-A | Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds | PHARMACIA & UPJOHN COMPANY (US) | 1999-02-02 | — | — | US | disclosed |