SCHEMBL8410293

SCHEMBL8410293

NNC(=O)[C@@]1(C(=O)O)CCC[C@@H]1O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.37
CYP2C19 P33261 1/20 0.31
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5513195 0.95 DGAT1 (0.36) DGAT1CYP2C19
SCHEMBL8408705 0.95 DGAT1 (0.36) DGAT1CYP2C19
SCHEMBL5513198 0.85 DGAT1 (0.39) DGAT1
SCHEMBL28053195 0.82 CYP2C19 (0.38) CYP2C19
SCHEMBL27659634 0.76 CYP2C19 (0.41) CYP2C19
SCHEMBL10723648 0.75 GRM2 (0.33) DGAT1CYP2C19
SCHEMBL7899652 0.73 CYP2C19 (0.34) DGAT1CYP2C19
SCHEMBL28324101 0.68 FFAR3 (0.33) CYP2C19
SCHEMBL8404679 0.67 CYP2C19 (0.37) CYP2C19
SCHEMBL7401320 0.67 CYP2C19 (0.37) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942644-A Precursors for the production of chiral vicinal aminoalcohols BIOCATALYTICS, INC. (US) 1999-08-24 US disclosed