Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896981 | 1.00 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5897200 | 1.00 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5896984 | 1.00 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5896975 | 1.00 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5897196 | 1.00 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5897120 | 0.95 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8408707 | 0.95 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5897128 | 0.95 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5897133 | 0.95 | ALDH1A1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3623530 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942644-A | Precursors for the production of chiral vicinal aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |