Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | XDH | P47989 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410464 | 0.93 | ATAD2 (0.55) | ATAD2CA12CA1CA2CA9 | |
| SCHEMBL2723920 | 0.89 | TSHR (0.53) | ATAD2CA12CA1CA2CA9 | |
| SCHEMBL654773 | 0.89 | CA1 (0.58) | ATAD2CA12CA1CA2CA9 | |
| SCHEMBL111187 | 0.89 | CA12 (0.58) | ATAD2CA12CA1CA2CA9 | |
| SCHEMBL310741 | 0.88 | ATAD2 (0.58) | ATAD2CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL9494959 | 0.87 | CA1 (0.56) | ATAD2CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL111186 | 0.87 | CA12 (0.56) | ATAD2CA12CA1CA2CA9 | |
| SCHEMBL18172349 | 0.87 | MAPT (0.50) | ATAD2CA12CA1CA2CA9 | |
| SCHEMBL21253164 | 0.87 | ATAD2 (0.50) | ATAD2CA12CA1CA2CA9 | |
| SCHEMBL2685786 | 0.87 | ATAD2 (0.53) | ATAD2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714879-B1 | Biphenyl iodinated derivatives and their diagnostic use | BRACCO SPA (IT) | 1999-08-04 | — | — | EP | disclosed |
| US-5663413-A | X-RAY CONTRAST | DIBRA S.P.A. (IT) | 1997-09-02 | — | — | US | disclosed |
| EP-0714879-A1 | Biphenyl iodinated derivatives and their diagnostic use | BRACCO S.p.A. (IT) | 1996-06-05 | — | — | EP | disclosed |